NOVEL 2,5-DIHYDROFURYL-GAMMA-LACTAM DERIVATIVES FROM HEMEROCALLIS-FULVA L VAR KWANZO REGEL

被引：27

作者：

INOUE, T ^{[1
]}

IWAGOE, K ^{[1
]}

KONISHI, T ^{[1
]}

KIYOSAWA, S ^{[1
]}

FUJIWARA, Y ^{[1
]}

机构：

[1] KYOTO PHARMACEUT UNIV, NAKAUCHI CHO, MISASAGI YAMASHINA KU, KYOTO 607, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1990年 / 38卷 / 11期

关键词：

5-dihydrofuryl-γ-lactam; !sup]1[!/sup]H-NMR; Ehrlich reaction; Hemerocallis fulva var. kwanzo 2; Liliaceae; NOE;

D O I：

10.1248/cpb.38.3187

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three novel 2,5-dihydrofuryl-r-lactam derivatives, fulvanine A, B and C, have been extracted from Hemerocallis fulva L. var. kwanzo Regel along with compound I. Their respective structures have been established as 1-(3-hydroxymethyl-2,5-dihydrofuryl)-azacyclopenta-3,5-dihydroxy-2-one, 1-(3-methyl-2,5-dihydrofuryl)-azacyclopenta-3,5-dihydroxy-2-one and 1 — (3—methyl-2,5-dihydrofuryl)-azacyclopenta-3-hydroxy-5-methoxy-2-one. Compound I was found its 1 13 H and C-NMR spectra to be identical to oxypinnatanine. © 1990, The Pharmaceutical Society of Japan. All rights reserved.

引用

页码：3187 / 3189

页数：3