STOICHIOMETRY OF AMINOACYL-TRANSFER RNA BINDING AND GTP CLEAVAGE DURING CHAIN ELONGATION AND TRANSLOCATION

被引：34

作者：

ONO, Y

SKOULTCHI, A

WATERSON, J

LENGYEL, P

机构：

来源：

NATURE | 1969年 / 223卷 / 5207期

关键词：

D O I：

10.1038/223697a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

One GTP molecule is cleaved for each aminoacyl-transfer RNA molecule bound to the ribosome during peptide chain elongation. Cleavage of further GTP is needed for translocation. © 1969 Nature Publishing Group.

引用

页码：697 / +

页数：1

共 26 条

[1] TRANSLOCATION IN PROTEIN SYNTHESIS - A HYBRID STRUCTURE MODEL [J].

BRETSCHER, MS .

NATURE, 1968, 218 (5142) :675-+

[2] EFFECT OF A SOLUBLE TRANSFER FACTORS ON REACTION OF AMINOACYL-TRNA WITH PUROMYCIN [J].

BROT, N ;

ERTEL, R ;

WEISSBACH, H .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1968, 31 (04) :563-+

[3] CHARACTERIZATION OF A RIBOSOME-LINKED GUANOSINE TRIPHOSPHATASE IN ESCHERICHIA COLI EXTRACTS [J].

CONWAY, TW ;

LIPMANN, F .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1964, 52 (06) :1462-&

[4] INITIATION AND PROTEIN SYNTHESIS - TRANSLATION OF DI-AND TRICODON MESSENGERS [J].

ERBE, RW ;

LEDER, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1968, 31 (05) :798-&

[5] ROLE OF GTP IN PROTEIN SYNTHESIS - INTERACTION OF GTP WITH SOLUBLE TRANSFER FACTORS FROM E COLI [J].

ERTEL, R ;

REDFIELD, B ;

BROT, N ;

WEISSBACH, H .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1968, 128 (02) :331-+

[6] SPARSOMYCIN INHIBITION OF POLYPEPTIDE SYNTHESIS PROMOTED BY SYNTHETIC AND NATURAL POLYNUCLEOTIDES [J].

GOLDBERG, IH ;

MITSUGI, K .

BIOCHEMISTRY, 1967, 6 (02) :372-+

[7] STEPWISE SYNTHESIS OF A TRIPEPTIDE [J].

HAENNI, A ;

LUCASLEN.J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1968, 61 (04) :1363-&

[8] BEHAVIOUR OF ACETYLPHENYLALANYL SOLUBLE RIBONUCLEIC ACID IN POLYPHENYLALANINE SYNTHESIS [J].

HAENNI, AL ;

CHAPEVILLE, F .

BIOCHIMICA ET BIOPHYSICA ACTA, 1966, 114 (01) :135-+

[9] A COMPETITIVE INHIBITOR OF GTP REACTION IN PROTEIN SYNTHESIS [J].

HERSHEY, JWB ;

MONRO, RE .

JOURNAL OF MOLECULAR BIOLOGY, 1966, 18 (01) :68-&

[10] ASSOCIATION OF FUSIDIC ACID SENSITIVITY WITH G FACTOR IN A PROTEIN-SYNTHESIZING SYSTEM [J].

KINOSHITA, T ;

KAWANO, G ;

TANAKA, N .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1968, 33 (05) :769-+

← 1 2 3 →