NEUROPHARMACOLOGY AND DRUG-INTERACTIONS IN CLINICAL-PRACTICE

被引：9

作者：

GRAVES, NM

机构：

[1] College of Pharmacy, University of Minnesota, Minneapolis, Minnesota

来源：

EPILEPSIA | 1995年 / 36卷

关键词：

ANTICONVULSANTS; PHARMACOKINETICS; DRUG INTERACTIONS;

D O I：

10.1111/j.1528-1157.1995.tb05997.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Absorption, distribution, and clearance are key pharmacokinetic principles. These parameters can be highly variable among patients and among compounds, and are factors that must be considered in the wide variability in response to medications. Current antiepileptic drugs (AEDs) present many challenges in their administration. However, understanding and utilizing pharmacokinetic principles can assist the clinician in the appropriate optimization of AEDs.

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页码：S27 / S33

页数：7

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