POLYMER-SUPPORTED CHIRAL PROMOTERS FOR THE ASYMMETRIC ALDOL REACTION OF BENZALDEHYDE WITH SILYL KETENE ACETAL

被引：18

作者：

KIYOOKA, S

KIDO, Y

KANEKO, Y

机构：

[1] Department of Chemistry, Kochi University, Kochi, 780, Akebono-cho

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 29期

关键词：

D O I：

10.1016/S0040-4039(00)77074-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral polymers (A and B) having pendant alpha-amino acid moiety were prepared by suspension copolymerization. A polymer-supported chiral borane, formed from chiral polymer A and BH3.THF, effectively promoted the aldol reaction in THF of benzaldehyde with silyl ketene acetal in a similar enantioselectivity to that using the corresponding soluble counterpart. Some interesting polymer effects were also found on solvent and reaction temperature. .

引用

页码：5243 / 5246

页数：4

共 16 条

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