A STEREOCONTROLLED APPROACH TO 1-BETA-METHYLCARBAPENEM

被引：33

作者：

DAVIES, SG ^{[1
]}

HEDGECOCK, CJR ^{[1
]}

MCKENNA, JM ^{[1
]}

机构：

[1] ROUSSEL LABS LTD,SWINDON SN3 5BZ,WILTS,ENGLAND

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 04期

关键词：

D O I：

10.1016/0957-4166(95)00079-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Conjugate addition of lithium N-allyl-N-alpha-methylbenzylamide to chiral alpha,beta-unsaturated esters is subject to double stereodifferentiation, the mismatched pair reaction allowing access to an intermediate for 1 beta-methylcarbapenem synthesis.

引用

收藏

页码：827 / 830

页数：4

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