MOLECULAR-GENETICS OF ANTIGENIC VARIATION

被引:69
作者
BORST, P
机构
[1] The Netherlands Cancer Institute, 1066 CX Amsterdam
来源
IMMUNOPARASITOLOGY TODAY-A COMBINED ISSUE OF IMMUNOLOGY TODAY AND PARASITOLOGY TODAY | 1991年 / 03期
关键词
D O I
10.1016/S0167-5699(05)80009-X
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Antigenic variation is one of the most effective strategies developed by parasites to escape immune destruction. It requires a large wardrobe of surface coats and mechanisms to exchange one coat for an unrelated one. The molecular principles of antigenic variation are now largely known in the bacterial species Borrelia and Neisseria and in the protozoa of the African trypanosome group and these three examples are discussed here by Piet Borst. © 1991 Elsevier Science Publishers Ltd, UK.
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页码:A29 / A33
页数:5
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