ANTI-TUMOUR EFFECT OF CHLORAMBUCIL - ANTIBODY COMPLEXES IN A MURINE MELANOMA SYSTEM

被引：9

作者：

DULLENS, HF ^{[1
]}

DEWEGER, RA ^{[1
]}

VENNEGOOR, C ^{[1
]}

DENOTTER, W ^{[1
]}

机构：

[1] NETHERLANDS CANC INST,AMSTERDAM,NETHERLANDS

来源：

EUROPEAN JOURNAL OF CANCER | 1979年 / 15卷 / 01期

关键词：

D O I：

10.1016/0014-2964(79)90207-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

An anti-serum against a transplantable murine melanoma (Harding Passey melanoma; HPM) was raised in rabbits. The IgG fraction of the anti-serum was non-covalently linked to chlorambucil. The chlorambucil-antibody complex was tested in BALB/c mice injected i.p. with HMP cells. The complex had considerably more anti-tumour effect than the unlinked components. © 1979.

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页码：69 / 75

页数：7

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