A SIMPLE, STEREOSPECIFIC SYNTHESIS OF DL-MUSCARINE AND DL-ALLOMUSCARINE

被引：20

作者：

MATSUMOT.T

ICHIHARA, A

ITO, N

机构：

[1] Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo

来源：

TETRAHEDRON | 1969年 / 25卷 / 24期

关键词：

D O I：

10.1016/S0040-4020(01)83096-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A bromolactone (VII) was stereospecifically converted to a tetrabydrofuran (IVa, Me/CO2H cis) and a dimethylamide (VIII, Me/CONMe2 trans. Possible mechanisms for these reactions are discussed. Since IVa and VIII have been transformed to dl-muscarine (I) and dl-allomuscarine (II) respectively, stereospecific formation of IVa and VIII provides a stereospecific synthesis of these muscarines. © 1969.

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页码：5889 / &

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