RECENT DEVELOPMENTS ON THE MECHANISM OF CHEMICAL CARCINOGENESIS BY AROMATIC-HYDROCARBONS

被引：37

作者：

PULLMAN, B

机构：

[1] Institut de Biologie Physico-Chimique, Laboratoire de Biochimie Théorique, Associé au Centre National de la Recherche Scientifique, Paris, F- 75005, 13, rue P. et M. Curie

来源：

INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY | 1979年 / 16卷 / 03期

关键词：

D O I：

10.1002/qua.560160321

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

This paper presents a critical discussion of recent discoveries on the metabolic transformations of polycyclic aromatic hydrocarbons and their interactions with nucleic acids in the light of quantum‐mechanical theories of chemical carcinogenesis. Copyright © 1979 John Wiley & Sons, Inc.

引用

页码：669 / 689

页数：21

共 94 条

[1] STRUCTURAL FEATURES WHICH DETERMINE CARCINOGENESIS, MUTAGENESIS, AND RATES OF ACID-MEDIATED AND WATER-MEDIATED SOLVOLYSIS OF AND NUCLEOPHILIC-ATTACK UPON DIOL EPOXIDES, BAY-REGION AND NON-BAY-REGION TETRAHYDRO EPOXIDES, AND K-REGION AND NON-K-REGION ARENE OXIDES [J].

BECKER, AR ;

JANUSZ, JM ;

ROGERS, DZ ;

BRUICE, TC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (10) :3244-3246

[2]

BERGER GD, 1978, TETRAHEDRON LETT, P231

[3] PRODUCTS OBTAINED AFTER INVITRO REACTION OF 7,12-DIMETHYLBENZ[A]ANTHRACENE 5,6-OXIDE WITH NUCLEIC-ACIDS [J].

BLOBSTEIN, SH ;

WEINSTEIN, IB ;

GRUNBERGER, D ;

WEISGRAS, J ;

HARVEY, RG .

BIOCHEMISTRY, 1975, 14 (15) :3451-3458

[4] 8,9-DIHYDRO-8,9-DIHYDROXYBENZ(A)ANTHRACENE 10,11-OXIDE - NEW TYPE OF POLYCYCLIC AROMATIC HYDROCARBON METABOLITE [J].

BOOTH, J ;

SIMS, P .

FEBS LETTERS, 1974, 47 (01) :30-33

[5] METABOLIC CONVERSION OF BENZO[ALPHA]PYRENE BY SYRIAN-HAMSTER LIVER-MICROSOMES AND BINDING OF METABOLITES TO DEOXYRIBONUCLEIC ACID [J].

BORGEN, A ;

DARVEY, H ;

CASTAGNO.N ;

CROCKER, TT ;

RASMUSSE.RE ;

WANG, IY .

JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (05) :502-506

[6]

BROOKES P, 1972, POLYCYCLIC HYDROCARB, V2, P4

[7] NUCLEOPHILIC DISPLACEMENT ON ARENE OXIDES OF PHENANTHRENE [J].

BRUICE, PY ;

BRUICE, TC ;

YAGI, H ;

JERINA, DM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (10) :2973-2981

[8]

BUENING KK, P NATL ACAD SCI US

[9]

CALVIN M, 1975, FEBS LETT, V57, P250

[10] FLUORESCENCE SPECTRAL EVIDENCE THAT BENZO(A)PYRENE-DNA PRODUCTS IN MOUSE SKIN ARISE FROM DIOL-EPOXIDES [J].

DAUDEL, P ;

DUQUESNE, M ;

VIGNY, P ;

GROVER, PL ;

SIMS, P .

FEBS LETTERS, 1975, 57 (03) :250-253

← 1 2 3 4 5 6 7 8 9 10 →