IMMUNOHISTOCHEMICAL LOCALIZATION OF CYCLIC-GMP IN AGGREGATING POLYSPHONDYLIUM-VIOLACEUM

被引：7

作者：

PAN, P

WEDNER, HJ

机构：

[1] PRINCETON UNIV,DEPT BIOL,PRINCETON,NJ 08540

[2] WASHINGTON UNIV,SCH MED,DEPT MED,DIV IMMUNOL,ST LOUIS,MO 63110

来源：

DIFFERENTIATION | 1979年 / 14卷 / 1-2期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1111/j.1432-0436.1979.tb01019.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Using indirect immunofluorescence technique, it has been possible to localize cyclic GMP in Polysphondylium violaceum cells. The bound cyclic nucleotide is localized throughout the cell during early stages, however, this staining increases and there is marked localization of cyclic GMP in the nuclear areas of the cells when aggregation is in full swing. Over 90% of the cells exhibited intense nuclear staining by 6 h and this decreased to less than 10% by 10 h. © 1979, International Society of Differentiation. All rights reserved.

引用

页码：113 / 118

页数：6

共 29 条

[1]

BONNER JT, 1970, P NATL ACAD SCI USA, V65, P110

[2] EVIDENCE FOR THE FORMATION OF CELL AGGREGATES BY CHEMOTAXIS IN THE DEVELOPMENT OF THE SLIME MOLD DICTYOSTELIUM DISCOIDEUM [J].