THE PREFERENCE FOR SWITCHING TO EXPRESSION OF THE IGA ISOTYPE OF ANTIBODY EXHIBITED BY LYMPHOCYTES-B IN PEYER PATCHES IS LIKELY DUE TO INTRINSIC-PROPERTIES OF THEIR MICROENVIRONMENT

被引：16

作者：

CEBRA, JJ

LOGAN, AC

WEINSTEIN, PD

机构：

[1] Department of Biology, University of Pennsylvania, Philadelphia, 19104-6018, PA

来源：

IMMUNOLOGIC RESEARCH | 1991年 / 10卷 / 3-4期

关键词：

D O I：

10.1007/BF02919728

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The prompt switching to the expression of different non-IgM/IgD isotypes in PP and LN during acute, de novo GC reactions at the two types of sites suggests intrinsic differences in their microenvironments as the basis for isotype preference. © 1991 Humana Press Inc.

引用

页码：393 / 395

页数：3

共 6 条

[1]

BUTCHER EC, 1982, J IMMUNOL, V129, P2698

[2]

CEBRA JJ, 1980, J RETICULOENDOTHEL S, V28, P61

[3] GERMINAL CENTER B-CELLS - ANTIGEN-SPECIFICITY AND CHANGES IN HEAVY-CHAIN CLASS EXPRESSION [J].