ALBENDAZOLE FOR THE TREATMENT OF HUMAN GNATHOSTOMIASIS

被引：67

作者：

KRAIVICHIAN, P ^{[1
]}

KULKUMTHORN, M ^{[1
]}

YINGYOURD, P ^{[1
]}

AKARABOVORN, P ^{[1
]}

PAIREEPAI, CC ^{[1
]}

机构：

[1] MAHARAJRA HOSP,DEPT MED,NAKORN,THAILAND

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1992年 / 86卷 / 04期

关键词：

D O I：

10.1016/0035-9203(92)90248-B

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The efficacy of albendazole was investigated in 112 patients with symptomatic gnathostomiasis; 49 received 400 mg twice daily, 51 received 400 mg once daily, and 12 patients received placebo, all for 21 d. Subsequent follow-up was for 6 months. Cure (no further swelling) was seen in 93.9% and 94.1 % of the treatment groups but in none of the placebo group. Additionally, reductions in eosinophil counts and in immunoglobulin G antibody were observed after treatment. Side effects were minimal. Albendazole may be an effective compound for the treatment of gnathostomiasis.

引用

页码：418 / 421

页数：4

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