REGULATION OF OXIDATIVE ACTIVITY AND DELTA-PSI OF LIVER-MITOCHONDRIA OF ACTIVE AND HIBERNATING GOPHERS - THE ROLE OF PHOSPHOLIPASE-A2

被引:7
作者
BRUSTOVETSKY, NN
EGOROVA, MV
MAYEVSKY, EI
机构
[1] Institute of Theoretical and Experimental Biophysics, U.S.S.R. Academy of Sciences, Puschchino
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1992年 / 102卷 / 03期
关键词
D O I
10.1016/0305-0491(92)90059-Z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1. In the present work the initially lowered oxidase activity of liver mitochondria of hibernating gophers is shown to increase upon Ca2+-loading, after freezing-thawing repeated three times and after swelling in a medium containing potassium acetate as well as in a hypotonic sucrose medium. 2. In all cases the inhibition of phospholipase A2 hindered the increase of the oxidase activity of mitochondria. 3. Mitochondria of hibernating gophers have a lowered DELTA-PSI in comparison with active animals, which is restored in the hypotonic medium.
引用
收藏
页码:635 / 638
页数:4
相关论文
共 19 条