ASCORBIC-ACID AND EDTA TREATMENT OF LEAD TOXICITY IN RATS

被引：72

作者：

GOYER, RA

CHERIAN, MG

机构：

[1] Department of Pathology, Health Sciences Centre, University of Western Ontario, London

来源：

LIFE SCIENCES | 1979年 / 24卷 / 05期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0024-3205(79)90215-7

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Ascorbic acid given orally to lead exposed rats has similar chelating properties as equimolar amounts of parenterally administered EDTA. Ascorbic acid in combination with EDTA is more than twice as effective as either chelating agent given alone and the combination is particularly effective in removing lead from the central nervous system. © 1979.

引用

页码：433 / 438

页数：6

共 20 条

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CHISOLM, JJ
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[10] Holmes HN, 1939, J LAB CLIN MED, V24, P1119

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