SYNTHESIS OF OPTICALLY-ACTIVE CYCLOHEXENOL DERIVATIVES VIA ENZYME CATALYZED ESTER HYDROLYSIS OF 4-ACETOXY-3-METHYL-2-CYCLOHEXENONE

被引：40

作者：

POLLA, M ^{[1
]}

FREJD, T ^{[1
]}

机构：

[1] LUND INST TECHNOL,CTR CHEM,POB 124,S-22100 LUND,SWEDEN

来源：

TETRAHEDRON | 1991年 / 47卷 / 30期

关键词：

ENZYMATIC ESTER HYDROLYZES; 1,4-ADDITIONS; ALDOL-TYPE REACTIONS; ABSOLUTE CONFIGURATION DETERMINATION; CD;

D O I：

10.1016/S0040-4020(01)86539-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The optically active cyclohexenol derivatives 9a-d, and 10a-c are synthesized from (-)-6, which is obtained by enzymatic ester hydrolysis of racemic 8. Attempts towards the synthesis of the taxane skeleton are described.

引用

页码：5883 / 5894

页数：12

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