SPURIOUS HYPERCHLOREMIA AND DECREASED ANION GAP IN A PATIENT WITH DEXTROMETHORPHAN BROMIDE

被引：34

作者：

NG, YY ^{[1
]}

LIN, WL ^{[1
]}

CHEN, TW ^{[1
]}

LIN, BC ^{[1
]}

TSAI, SH ^{[1
]}

CHANG, CC ^{[1
]}

HUANG, TP ^{[1
]}

机构：

[1] NATL YANG MING MED COLL,TAIPEI,TAIWAN

来源：

AMERICAN JOURNAL OF NEPHROLOGY | 1992年 / 12卷 / 04期

关键词：

HYPERCHLOREMIA; BROMISM; NEGATIVE ANION GAP; DEXTROMETHORPHAN BROMIDE;

D O I：

10.1159/000168457

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Although cold syrup containing dextromethorpan bromide is widely administered, the bromism due to cold syrup has not been reported. We report a patient who had negative anion gap with hyperchloremia and conscious loss because of daily intake of cold complex syrup (containing dextromethorphan bromide 0.4 mg/ml, acetaminophen 8.33 mg/ml) for headache for 4-5 years. The bromide content in cold complex syrup resulted in serum levels of bromide that interfered with the automated analyzers for chloride content. When conscious change is due to bromism, hemodialysis instead of forced hydration and diuresis should be performed immediately. Therefore, patients with a markedly negative anion gap with hyperchloremia should be considered as having halide intoxication.

引用

页码：268 / 270

页数：3

共 8 条

[1]

ELIN RJ, 1981, CLIN CHEM, V27, P778

[2] CLINICAL USE OF ANION GAP [J].