ADENYL CYCLASE IN HUMAN PLATELETS - ACTIVITY AND RESPONSIVENESS

被引：109

作者：

ZIEVE, PD

GREENOUGH, WB

机构：

[1] Department of Medicine, Baltimore City Hospitals Baltimore, MD

[2] Johns Hopkins University, Baltimore, MD

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 35卷 / 04期

关键词：

D O I：

10.1016/0006-291X(69)90368-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hormonally responsive adenyl cyclase activity was measured in lysates of human platelets. Activity was stimulated by fluoride, prostaglandin E/, and glucagon; and was inhibited by thrombin, epinephrine, norepinephrine, and serotonin. The results suggest that adenosine-3/, 5/ monophosphate (cyclic AMP) may be important in the regulation of platelet adhesiveness. © 1969.

引用

页码：462 / +

页数：1

共 7 条

[1] BERGSTROM S, 1968, PHARMACOL REV, V20, P1
[2] BUTCHER RW, 1962, J BIOL CHEM, V237, P1244
[3] MARCUS AJ, 1965, PHYSIOLOGY BLOOD PLA, P52
[4] SUTHERLAND EW, 1962, J BIOL CHEM, V237, P1220
[5] SOME ASPECTS OF BIOLOGICAL ROLE OF ADENOSINE 3',5'-MONOPHOSPHATE (CYCLIC AMP)
SUTHERLAND, EW
ROBISON, GA
BUTCHER, RW
[J]. CIRCULATION, 1968, 37 (02) : 279 - +
[6] INTRACELLULAR PH OF HUMAN PLATELET
ZIEVE, PD
SOLOMON, HM
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1966, 45 (08) : 1251 - &
[7] EFFECT OF HEMATOPORPHYRIN AND LIGHT ON HUMAN PLATELETS .1. MORPHOLOGIC FUNCTIONAL AND BIOCHEMICAL CHANGES
ZIEVE, PD
SOLOMON, HM
KREVANS, JR
[J]. JOURNAL OF CELLULAR PHYSIOLOGY, 1966, 67 (02) : 271 - +

← 1 →