NO BENEFICIAL EFFECT OF SPLENECTOMY IN HEREDITARY HIGH RED-CELL MEMBRANE PHOSPHATIDYLCHOLINE HEMOLYTIC-ANEMIA - CLINICAL AND MEMBRANE STUDIES OF 20 PATIENTS

被引：9

作者：

OTSUKA, A ^{[1
]}

SUGIHARA, T ^{[1
]}

YAWATA, Y ^{[1
]}

机构：

[1] KAWASAKI MED SCH, SCH MED, DEPT MED, DIV HEMATOL, KURASHIKI, OKAYAMA 70101, JAPAN

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 1990年 / 34卷 / 01期

关键词：

D O I：

10.1002/ajh.2830340104

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The clinical features and red cell membrane characteristics of 20 patients with hereditary high red cell membrane phosphatidylcholine hemolytic anemia (HPCHA) were studied in relation to the effect of splenectomy. After splenectomy, anemia worsened and the extent of increased hemolysis in these patients was unchanged, indicating a contraindication for splenectomy. Concomitant with these results in clinical hematology, marked stomatocytic changes, increased red cell phosphatidylcholine content, and enhanced sodium transport, which were observed before splenectomy, were not improved by splenectomy. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company

引用

页码：8 / 14

页数：7

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