ON SPINAL OSTEOCHONDROMAS

被引:160
作者
ALBRECHT, S
CRUTCHFIELD, JS
SEGALL, GK
机构
[1] BAYLOR COLL MED,METHODIST HOSP,DEPT PATHOL,MS 205,6565 FANNIN ST,HOUSTON,TX 77030
[2] BAYLOR COLL MED,METHODIST HOSP,DEPT NEUROSURG,HOUSTON,TX 77030
关键词
OSTEOCHONDROMA; SPINAL NEOPLASM; BONE TUMOR;
D O I
10.3171/jns.1992.77.2.0247
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Osteochondromas (or osteocartilaginous exostoses) make up about 30% to 40% of benign bone tumors. Most are solitary lesions but some are multiple, usually with autosomal dominant inheritance. From 1% to 4% of osteochondromas occur in the spine, where they can cause a variety of signs and symptoms, including those of spinal cord or spinal root compression. The authors present five patients with osteochondromas of the spine and review the findings together with those of over 130 cases reported since 1907. The cases were divided into: 1) spinal osteochondromas in patients with multiple osteochondromas, and 2) solitary osteochondromas occurring in the spine. The age (mean +/- standard error of the mean) of patients in the first group was 21.6 +/- 1.8 years compared to 30.0 +/- 2.1 years for those in the second group (p < 0.02). There was a significant male predominance overall (M:F = 2.5:1; p < 0.0005). In both groups, one-half of the lesions involved the cervical spine. Symptoms are caused by pressure on adjacent structures. Spinal cord compression was reported more than twice as frequently in the multiple osteochondroma group as in the single osteochondroma group (77% vs 33%; p < 0.0005). Computerized tomography (CT) is the imaging procedure of choice. In both groups, the majority of surgically treated patients (90% and 88%, respectively) improve, with about three-quarters of the improved patients having no residual disease or only minor deficits.
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页码:247 / 252
页数:6
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