THE FATE OF THE HYDROGENS OF D-GLUCOSE DURING THE LIPID BIOSYNTHESIS AND STEREOCHEMISTRY OF THE TRIOSE-PHOSPHATE ISOMERASE REACTION IN ARCHAEBACTERIA HALOBACTERIUM-HALOBIUM

被引：5

作者：

KAKINUMA, K

TAKAGI, I

EGUCHI, T

机构：

[1] Department of Chemistry, Tokyo Institute of Technology O-okayama, Meguro-ku, Tokyo

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 43期

关键词：

D O I：

10.1016/S0040-4039(00)79020-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereochemistry of the triose phosphate isomerase reaction in the halophilic archaebacteria Halobacterium was determined for the first time by virtue of the biosynthesis of the core membrane lipid. sn-2,3-di-O-phytanyl glycerol. Feeding experiments with D-[4-H-2]- and D-[5-H-2]glucose,followed by 500 MHz H-1-NMR comparison of the resulting membrane lipids with the chemically synthesized deuterated standards appeared to show that the 3R hydrogen of dihydroxyacetone-phosphate is exchangeable with a medium.

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页码：6479 / 6482

页数：4

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