DIAGNOSTIC-VALUE OF THE ORAL PANCREATIC FUNCTION-TEST

被引：18

作者：

MITCHELL, CJ ^{[1
]}

HUMPHREY, CS ^{[1
]}

BULLEN, AW ^{[1
]}

KELLEHER, J ^{[1
]}

机构：

[1] UNIV LEEDS,ST JAMES HOSP,DEPT SURG,LEEDS LS9 7TF,W YORKSHIRE,ENGLAND

来源：

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 1979年 / 14卷 / 02期

关键词：

Bowel disease; Liver disease; N-benzoyl-L-tyrosyl-p-aminobenzoic acid; Oral pancreatic function test; Pancreatitis;

D O I：

10.3109/00365527909179867

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

An oral pancreatic function test (PFT) using the synthetic peptide N-benzoyl-L-tyrosyl-p-aminobenzoic acid can assess pancreatic exocrine function, since urinary recovery of the ingested dose is an indirect index of chymotryptic activity. We have studied 34 subjects using this oral PFT, which correctly distinguished the control group (8 subjects) from the pancreatitis group (10 patients), results correlating well with Lundh test findings. However, the test was falsely abnormal on 9 out of 16 occasions in patients with bowel or liver disease. We therefore conclude that the present test cannot distinguish small-bowel disease from pancreatic disease, which is often the diagnostic problem, and is also frequently falsely abnormal in the presence of chronic liver disease. © 1979 Informa UK Ltd.

引用

页码：183 / 187

页数：5

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