MALARIA IN NIGERIA - A REVISIT

被引:88
作者
SALAKO, LA
AJAYI, FO
SOWUNMI, A
WALKER, O
机构
[1] UNIV COLL HOSP IBADAN,CLIN PHARMACOL UNIT,IBADAN,NIGERIA
[2] OGUN STATE UNIV,DEPT PHARMACOL,SAGAMU,NIGERIA
来源
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY | 1990年 / 84卷 / 05期
关键词
D O I
10.1080/00034983.1990.11812493
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The frequency of asymptomatic malaria parasitaemia was investigated in rural and urban school-children aged six to 12 years in southwestern Nigeria between January 1987 and October 1988. Asymptomatic parasitaemia as detected in the rural school-children all year round with the lowest parasite rate in January and the highest in July, corresponding to the mid-dry and wet seasons respectively. Asymptomatic parasitaemia was also common amongst urban school-children, but the frequency was lower than in the rural children. Parasite density was ≤ 1000 μl-1 in 42% of parasite-positive asymptomatic children and was > 10 000 μl-1 in only 20% of them. Mass treatment with chloroquine, to which the parasites were fully sensitive, was followed by the same rate of re-infection in the parasite-positive and parasite-negative groups. Of 7713 patients clinically diagnosed as having malaria 4425 were found to have parasitologically-proven malaria, and of these 4239 had pure Plasmodium falciparum malaria. Of the patients with falciparum malaria only 4.6% were below the age of one year. In 47% the parasite count was ≤ 1000 μl-1, and it was over 10 000 μl-1 1n 37% and over 250 000 μl-1 in 16%. There was no significant difference between the asymptomatic children and the acutely ill patients in the percentage with parasite densities ≤ 1000 μl-1, but the percentage with parasite densities > 10 000 μl-1 was significantly greater in the acute malaria patients than in those with asymptomatic parasitaemia.
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页码:435 / 445
页数:11
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