PEPTIDE CHLOROMETHYL KETONES AS IRREVERSIBLE INHIBITORS OF ELASTASE

被引：60

作者：

THOMPSON, RC ^{[1
]}

BLOUT, ER ^{[1
]}

机构：

[1] HARVARD UNIV, MED SCH, DEPT BIOL CHEM, BOSTON, MA 02115 USA

来源：

BIOCHEMISTRY | 1973年 / 12卷 / 01期

关键词：

D O I：

10.1021/bi00725a008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：44 / 47

页数：4

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共 21 条

[1] ACTIVE SITE OF ELASTASE - PARTIAL MAPPING BY MEANS OF SPECIFIC PEPTIDE SUBSTRATES
ATLAS, D
LEVIT, S
SCHECHTER, I
BERGER, A
[J]. FEBS LETTERS, 1970, 11 (04) : 281 - +
[2] CRESTFIELD AM, 1963, J BIOL CHEM, V238, P2413
[3] Hirs C.H.W., 1967, METHOD ENZYMOL, V11, P197
[4] A COMPARISON OF PROPERTIES OF ALPHA-LYTIC PROTEASE OF SORANGIUM-SP AND PORCINE ELASTASE
KAPLAN, H
SYMONDS, VB
DUGAS, H
WHITAKER, DR
[J]. CANADIAN JOURNAL OF BIOCHEMISTRY, 1970, 48 (06): : 649 - &
[5] KITZ R, 1962, J BIOL CHEM, V237, P3245
[6] SUBTILISIN BPN' - INACTIVATION BY CHLOROMETHYL KETONE DERIVATIVES OF PEPTIDE SUBSTRATES
MORIHARA, K
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1970, 138 (02) : 526 - &
[7] ISOLATION AND CHARACTERIZATION OF ALKYLATED HISTIDINE FROM TLCK INHIBITED TRYPSIN
PETRA, PH
COHEN, W
SHAW, EN
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1965, 21 (06) : 612 - &
[8] DESIGN AND SYNTHESIS OF INHIBITORS FOR CRYSTALLOGRAPHIC STUDIES ON ACTIVE SITE OF CHYMOTRYPSIN
POWERS, JC
WILCOX, PE
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1970, 92 (06) : 1782 - &
[9] REACTIVITY OF HIS-57 CHYMOTRYPSIN TO ALKYLATION
SHAW, E
RUSCICA, J
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1971, 145 (02) : 484 - &
[10] SHAW E, 1967, METHOD ENZYMOL, V11, P677