EVALUATION OF GLUTATHIONE-S-TRANSFERASE-PI IN NONINVASIVE DUCTAL CARCINOMA OF BREAST

被引：17

作者：

BELLAMY, COC

HARRISON, DJ

机构：

[1] Department of Pathology, University Medical School, Edinburgh

来源：

BRITISH JOURNAL OF CANCER | 1994年 / 69卷 / 01期

关键词：

D O I：

10.1038/bjc.1994.31

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Glutathione S-transferase Pi (GST P) has been reported to be a marker of dysplastic lesions. For this reason expression of GST P by intraduct breast carcinoma was evaluated by immunohistochemistry. Thirty-seven of 92 carcinomas (40%) were GST P positive. GST P staining did not correlate with histological variables, c-erbB-2 overexpression or with clinical outcome. The GST P status of recurrences did not correlate with that of the index lesion. There is little evidence that GST P is a useful marker of the potential of intraduct breast carcinoma to become invasive.

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页码：183 / 185

页数：3

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