ORGANOSPECIFIC ACTIVATION OF AZATHIOPRINE IN MICE - ROLE OF LIVER-METABOLISM IN MUTATION-INDUCTION

被引：12

作者：

HRELIA, P ^{[1
]}

MURELLI, L ^{[1
]}

SCOTTI, M ^{[1
]}

PAOLINI, M ^{[1
]}

CANTELLIFORTI, G ^{[1
]}

机构：

[1] UNIV BOLOGNA,IST FARMACOL,VIA IRNERIO 48,I-40126 BOLOGNA,ITALY

来源：

CARCINOGENESIS | 1988年 / 9卷 / 06期

关键词：

D O I：

10.1093/carcin/9.6.1011

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1011 / 1015

页数：5

共 32 条

[1]

[Anonymous], [No title captured]

[2] AZATHIOPRINE, A CLASTOGEN IN HUMAN SOMATIC-CELLS - ANALYSIS OF CHROMOSOME-DAMAGE AND SCE IN LYMPHOCYTES AFTER EXPOSURE INVIVO AND INVITRO [J].

APELT, F ;

KOLINGERRESHEIM, J ;

BAUCHINGER, M .

MUTATION RESEARCH, 1981, 88 (01) :61-72

[3]

BURNET FM, 1970, PROG EXP TUMOR RES, V13, P1

[4]

CANTELLIFORTI G, 1985, DRUGS EXP CLIN RES, V11, P123

[5]

CANTELLIFORTI G, 1987, ARCH TOXICOL S, V11, P204

[6]

CANTELLIFORTI G, 1984, MUTAT RES, V129, P291

[7] DEVELOPMENT OF LYMPHOMAS IN MICE WITH AUTOIMMUNE DISORDERS TREATED WITH AZATHIOPRINE [J].

CASEY, TP .

BLOOD, 1968, 31 (03) :396-&

[8] STUDIES ON MECHANISM OF FORMATION OF 5-MERCAPTO-1-METHYL-4-NITROIMIDAZOLE, A METABOLITE OF IMMUNOSUPPRESSIVE DRUG AZATHIOPRINE [J].

CHALMERS, AH .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (13) :1891-1901

[9] MUTAGENICITY OF AZATHIOPRINE IN MICE, DROSOPHILA-MELANOGASTER AND NEUROSPORA-CRASSA [J].

CLARK, JM .

MUTATION RESEARCH, 1975, 28 (01) :87-99

[10]

ELION GB, 1975, HDB EXP PHARMAKOL, V48, P404

← 1 2 3 4 →