REDUCTION OF BETA-HYDROXY KETONES WITH CATECHOLBORANE - A STEREOSELECTIVE APPROACH TO THE SYNTHESIS OF SYN 1,3-DIOLS

被引：143

作者：

EVANS, DA

HOVEYDA, AH

机构：

[1] Department of Chemistry, Harvard University, Cambridge

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 18期

关键词：

D O I：

10.1021/jo00305a005

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

: The stereoselective reduction of acyclic β-hydroxy ketones to syn 1,3-diols may be achieved with the mild reducing agent catecholborane. In certain instances reaction stereoselectivity may be enhanced through rhodium(I) catalysis. © 1990, American Chemical Society. All rights reserved.

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页码：5190 / 5192

页数：3

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