RED-CELL GLYOXALASE-I POLYMORPHISM AMONG THE SELECTED TRIBES OF THE SUDAN

850 unrelated subjects of both sexes from several tribes of Arab and Negroid origin in Sudan were investigated for the distribution of red cell GLOI phenotypes. The estimated frequency of GLO1 were from 0.3804 to 0.4121 in tribes of Arab extraction and 0.3000 to 0.3732 in tribes of Negroid origin. Hwazma tribe claiming Arab descent had a low frequency of GLO1 (0.2548). There was a significant deviation of Hardy-Weinberg equilibrium in the gene frequencies with excess of homozygosity in the present population groups probably due to the presence of high degree of inbreeding. There was no significant association of GLO phenotypes with haemoglobin types. © 1979 Business Center for Academic Societies.