INTRAVAGINAL INOCULATION OF MICE WITH THE CHLAMYDIA-TRACHOMATIS MOUSE PNEUMONITIS BIOVAR RESULTS IN INFERTILITY

被引:165
作者
DELAMAZA, LM
PAL, S
KHAMESIPOUR, A
PETERSON, EM
机构
关键词
D O I
10.1128/IAI.62.5.2094-2097.1994
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In an attempt to establish a model of chlamydial ascending salpingitis and infertility, three inbred strains of mice, C3H/HeN (H-2(k)), C57Bl/6N (H-2(b)), and BALB/cAnN (H-2(d)), were inoculated intravaginally with 3 X 10(7) inclusion-forming units of the Chlamydia trachomatis mouse pneumonitis biovar, Mice mated 6 weeks following inoculation were found to have a significant decrease in fertility rate compared with the control groups, as shown by a reduction in the number of pregnant mice and a decrease in the number of embryos.
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页码:2094 / 2097
页数:4
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