FLUOROCARBOHYDRATES .27. 2-DEOXY-2-FLUORO-L-FUCOSE - SYNTHESIS AND STRUCTURE

被引：10

作者：

BUTCHARD, CG ^{[1
]}

KENT, PW ^{[1
]}

机构：

[1] UNIV DURHAM, GLYCOPROT RES UNIT, DURHAM DH1 3HP, ENGLAND

来源：

TETRAHEDRON | 1979年 / 35卷 / 21期

关键词：

D O I：

10.1016/0040-4020(79)88019-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of CF3OF to 3,4-di-O-acetyl-L-fucal gave a 95% yield of 2 di-O-acetyl-2-deoxy-2-fluoro-L-fucosyl derivatives separable by column chromatography, both in crystalline form. The derivatives were identified by 1H and 19F-NMR to be the .alpha.-fluoride and the .alpha.-trifluoromethylglycoside. Acidic hydrolysis of either derivative gave the free sugar 2-deoxy-2-fluoro-L-fucose (non-crystalline), further characterized as the crystalline 1,3,4-tri-O-.alpha.-acetate.

引用

页码：2551 / 2554

页数：4

共 17 条

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