ONTOGENY OF TYPE-I AND TYPE-III DEIODINASE ACTIVITIES IN EMBRYONIC AND POSTHATCH CHICKS - RELATIONSHIP WITH CHANGES IN PLASMA TRIIODOTHYRONINE AND GROWTH-HORMONE LEVELS

被引：166

作者：

DARRAS, VM

VISSER, TJ

BERGHMAN, LR

KUHN, ER

机构：

[1] ERASMUS UNIV,SCH MED,DEPT INTERNAL MED 3,3000 DR ROTTERDAM,NETHERLANDS

[2] ERASMUS UNIV,SCH MED,DEPT CLIN ENDOCRINOL,3000 DR ROTTERDAM,NETHERLANDS

[3] CATHOLIC UNIV LEUVEN,NEUROENDOCRINOL & IMMUNOL BIOTECHNOL LAB,B-3000 LOUVAIN,BELGIUM

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-PHYSIOLOGY | 1992年 / 103卷 / 01期

关键词：

D O I：

10.1016/0300-9629(92)90252-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. The ontogeny of type I and type III deiodinase activities was studied in embryonic an posthatch chicks. 2. Hepatic type I activity showed a 3-fold increase up to the period of pipping and hatching and decreased slowly thereafter. 3. Hepatic type III activity increased by 3-fold from E14 to E17 and decreased more than 10-fold from E17 to C0. Posthatch levels were very low. 4. Type I activity in the kidney decreased slowly after hatching while type III activity was very low over the whole period studied. 5. Developmental changes during the late embryonic period suggest a causal relationship between the increase in plasma GH and T3 levels and the decrease in hepatic type III activity.

引用

页码：131 / 136

页数：6

共 23 条

[1] EVIDENCE FOR CHICKEN GH AS THE ONLY HYPOPHYSEAL FACTOR RESPONSIBLE FOR THE STIMULATION OF HEPATIC 5'-MONODEIODINATION ACTIVITY IN THE CHICK-EMBRYO [J].