OPTICAL RESOLUTION OF 1-ARYLETHANOLS WITH A CONDENSED AROMATIC RING BY LIPASE FROM PSEUDOMONAS-AERUGINOSA

被引：12

作者：

KATO, K

KATAYAMA, M

FUJII, S

KIMOTO, H

机构：

[1] Department of Chemistry, National Industrial Research Institute of Nagoya, Nagoya 462, Hirate-cho, Kita-ku

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1995年 / 59卷 / 11期

关键词：

D O I：

10.1271/bbb.59.2178

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Enantioselective syntheses of both enantiomers of 1-arylethanols with a condensed aromatic ring have been done through acetylation of the racemic alcohols with vinyl acetate in the presence of a lipase from Pseudomonas aeruginosa (Toyobo, LIP). The lipase LIP showed high enantioselectivity and reactivity for the title compounds, reacted acetates, and remaining alcohols were obtained with high optical purity.

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页码：2178 / 2180

页数：3

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