GLUCOSE-CONTROLLED INSULIN-DELIVERY SYSTEM - SEMI-SYNTHETIC INSULIN BOUND TO LECTIN

被引：229

作者：

BROWNLEE, M

CERAMI, A

机构：

来源：

SCIENCE | 1979年 / 206卷 / 4423期

关键词：

D O I：

10.1126/science.505005

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A stable, biologically active glycosylated insulin derivative that is complementary to the major combining site of concanavalin A has been synthesized. Hormone release is proportional to the quantity of glucose present. Glucose regulation of exogenous insulin delivery could have important applications in the therapy of diabetes mellitus. Copyright © 1979 AAAS.

引用

页码：1190 / 1191

页数：2

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