FIBRIN GLUE FROM SINGLE-DONATION AUTOLOGOUS PLASMAPHERESIS

被引：18

作者：

CASALI, B

RODEGHIERO, F

TOSETTO, A

PALMIERI, B

IMMOVILLI, R

GHEDINI, C

RIVASI, P

机构：

[1] SANTA MARIA HOSP, BLOOD TRANSFUS SERV, CTR TRANSFUS, VIALE RISORGIMENTO 80, I-42100 REGGIO EMILIA, ITALY

[2] SAN BORTOLO HOSP, DEPT HEMATOL, CTR HEMOPHILIA & THROMBOSIS, VICENZA, ITALY

[3] POLICLIN MODENA, CHIRURG CLIN, MODENA, ITALY

[4] MIRAMED, MODENA, ITALY

来源：

TRANSFUSION | 1992年 / 32卷 / 07期

关键词：

D O I：

10.1046/j.1537-2995.1992.32792391037.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A method is described for preparing fibrin glue from fibrinogen obtained by double cryoprecipitation of plasma collected by plasmapheresis. Plasma (average volume, 528.8 +/- 86 mL), collected from 12 plasmapheresis donors was cryoprecipitated twice. When the cryoprecipitated pellet was resuspended in 0.5 to 2 mL of saline (total volume of saline-resuspended fibrinogen: 5 mL), the average yield of fibrinogen was 78.4 +/- 18.3 mg per mL. This is comparable to commercial preparations, is suitable for clinical use, and offers greater safety at a reduced cost.

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页码：641 / 643

页数：3

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