ELECTROENCEPHALOGRAPHIC FINDINGS IN HASHIMOTOS ENCEPHALOPATHY

被引：110

作者：

HENCHEY, R ^{[1
]}

CIBULA, J ^{[1
]}

HELVESTON, W ^{[1
]}

MALONE, J ^{[1
]}

GILMORE, RL ^{[1
]}

机构：

[1] UNIV FLORIDA, COLL MED, DEPT NEUROL, GAINESVILLE, FL 32610 USA

来源：

NEUROLOGY | 1995年 / 45卷 / 05期

关键词：

D O I：

10.1212/WNL.45.5.977

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Hashimoto's encephalopathy (HE) is a steroid-responsive relapsing disorder that frequently presents with seizures and diffuse EEG abnormalities. We report the EEG findings in seven patients with encephalopathy, seizures, or both, associated with elevated antithyroid antibodies. There were several combinations of findings within the same patient and between patients. The EEGs of five patients had generalized slowing or frontal rhythmic slowing; two also had triphasic waves and one had periodic sharp waves. Three had focal left temporal slowing. HE is heterogeneous clinically and electrographically. A high level of suspicion is necessary to establish the diagnosis.

引用

页码：977 / 981

页数：5

共 10 条

[1]

Becker K.L., Ferguson R.H., The connective tissue diseases and symptoms associated with Hashimoto’s thyroiditis, N Engl J Med, 268, pp. 277-280, (1963)

[2]

Henderson L.M., Behan P.O., Aarli J., Hadley D., Draper I.T., Hashimoto’s encephalopathy: A new neuroimmunological syndrome, Ann Neurol, 22, pp. 140-141, (1987)

[3]

Shaw P.J., Walls T.J., Newman P.K., Cleland P.G., Cartlidge N., Hashimoto’s encephalopathy: A steroid-responsive disorder associated with high anti-thyroid antibody titers— report of 5 cases, Neurology, 41, pp. 228-233, (1991)

[4]

Mariotti S., Vitti P., Chiouato L., Recent advances in the understanding of humoral and cellular mechanisms implicated in thyroid autoimmune disorders, Clin Immunol Immuno- Pathol, 50, pp. S73-S84, (1989)

[5]

Flynn S.D., Nishiyama R.H., Bigos S.T., Autoimmune thyroid disease: Immunological, pathological and clinical aspects, Crit Rev Clin Lab Sei, 26, pp. 43-95, (1988)

[6]

Adams R.D., Victor M., Principles of Neurology, (1994)

[7]

Shein M., Apter A., Dickerman Z., Tyano S., Gadoth N., Encephalopathy in compensated Hashimoto’s thyroiditis: A clinical expression of autoimmune cerebral vasculitis, Brain Dev, 8, pp. 60-64, (1986)

[8]

Tonner D.R., Schlechte J.A., Neurologic complications of thyroid and parathyroid disease, Med Clin North Am, 77, pp. 251-263, (1993)

[9]

Karnaze D.S., Bickford R.G., Triphasic waves: A reassessment of their significance, Electroencephalogr Clin Neurophysiol, 57, pp. 193-198, (1984)

[10]

Jordan S.C., Johnston W.H., Bergstein J.M., Immune complex glomerulonephritis mediated by thyroid antigens, Arch Pathol Lab Med, 102, pp. 530-553, (1978)

← 1 →