CARDIOVASCULAR EFFECTS OF PAROXETINE

被引：38

作者：

KUHS, H

RUDOLF, GAE

机构：

[1] Department of Psychiatry, University of Münster, Münster, D-4400

来源：

PSYCHOPHARMACOLOGY | 1990年 / 102卷 / 03期

关键词：

Amitriptyline; Blood pressure; Electrocardiogram; Paroxetine; Plasma drug concentration; Systolic time intervals;

D O I：

10.1007/BF02244107

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In a double-blind clinical study, electrocardiogram, blood pressure and systolic time intervals were measured in 40 depressive patients treated with either paroxetine (30 mg/day) or amitriptyline (150 mg/day) for 6 weeks. While amitriptyline significantly increased the heart rate, the QTc interval and the PEP/LVET ratio, paroxetine did not alter any of the cardiovascular parameters measured. © 1990 Springer-Verlag.

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页码：379 / 382

页数：4

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