MALE HYPOSPADIAS, 625 CASES, ASSOCIATED MALFORMATIONS AND POSSIBLE ETIOLOGICAL FACTORS

被引:19
作者
SVENSSON, J
机构
[1] Department of Paediatric Surgery, Karolinska Sjukhuset, Stockholm
来源
ACTA PAEDIATRICA SCANDINAVICA | 1979年 / 68卷 / 04期
关键词
cryptorchidism; Hypospadias; lower urinary tract;
D O I
10.1111/j.1651-2227.1979.tb05060.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Abstract. Records from 625 patients with hypospadias have been reviewed, with reference to associated malformations. Cryptorchidism was found to be the most common associated malformation and was present in 6% of cases with hypospadias. The highest incidence of cryptorchidism was found in the more severe forms of hypospadias. Other concomitant genital malformations, such as bifid scrotum, hypoplasia of penis and remnants of the Müllerian system showed the same pattern. The recorded incidence of bifid scrotum and hypoplasia of the penis was 4% and 8% respectively. A high incidence of abnormalities in the lower urinary tract was found; 50 % of 84 patients investigated. The hypothesis of hypospadias being a result of testicular hormone insufficiency is discussed. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
收藏
页码:587 / 592
页数:6
相关论文
共 37 条
[1]  
AARSKOG D, 1971, Birth Defects Original Article Series, V7, P122
[2]  
AARSKOG D, 1970, ACTA PAEDIATR S S203
[3]   FETAL PLASMA TESTOSTERONE LEVELS AT MID-PREGNANCY AND AT TERM - RELATIONSHIP TO FETAL SEX [J].
ABRAMOVICH, DR ;
ROWE, P .
JOURNAL OF ENDOCRINOLOGY, 1973, 56 (03) :621-622
[4]   INCIDENCE OF HYPOSPADIAS IN SWEDEN [J].
AVELLAN, L .
SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY, 1975, 9 (02) :129-139
[5]  
BROWNE D, 1949, Postgrad Med J, V25, P367
[6]  
CENDRON J, 1964, P ROY SOC MED, V64, P125
[7]   GENETIC STUDIES ON HYPOSPADIAS IN MALES [J].
CHEN, YC ;
WOOLLEY, PV .
JOURNAL OF MEDICAL GENETICS, 1971, 8 (02) :153-+
[8]  
CRAWFORD BS, 1967, ANN R COLL SURG ENGL, V41, P32
[10]   INHERITANCE OF LIABILITY TO CERTAIN DISEASES ESTIMATED FROM INCIDENCE AMONG RELATIVES [J].
FALCONER, DS .
ANNALS OF HUMAN GENETICS, 1965, 29 :51-&