SLEEP-DEPRIVATION IN DEPRESSION - PATTERN OF RELAPSE AND CHARACTERISTICS OF PRECEDING SLEEP

被引：15

作者：

SOUTHMAYD, SE ^{[1
]}

DAVID, MM ^{[1
]}

CAIRNS, J ^{[1
]}

DELVA, NJ ^{[1
]}

LETEMENDIA, FJ ^{[1
]}

WALDRON, JJ ^{[1
]}

机构：

[1] QUEENS UNIV,DEPT PSYCHIAT,KINGSTON K7L 3N6,ONTARIO,CANADA

来源：

BIOLOGICAL PSYCHIATRY | 1990年 / 28卷 / 11期

关键词：

D O I：

10.1016/0006-3223(90)90063-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The pattern of relapse following therapeutic response to 40-hr sleep deprivation (SD) was examined in nine depressed patients. On the night ending SD patients were awakened from polygraphically recorded sleep on one or more occassions, in order to assess the clinical state. All subjects were found to demonstrate a precipitous and full relapse over this night, the timing of the relapse varying considerably between individuals. No association was found between deterioration in the clinical state and characteristics of preceding sleep. These results are consistent with the notion that, in predisposed individuals, some process associated with sleep has a depressogenic effect. However, they necessitate revision of theories of SD and depression that emphasize the infrastructure of sleep. © 1990.

引用

页码：979 / 988

页数：10

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