TRANSFER OF PHOSPHOLIPIDS BETWEEN THE ENDOPLASMIC-RETICULUM AND MITOCHONDRIA IN RAT HEPATOCYTES INVIVO

被引：22

作者：

EGGENS, I ^{[1
]}

VALTERSSON, C ^{[1
]}

DALLNER, G ^{[1
]}

ERNSTER, L ^{[1
]}

机构：

[1] KAROLINSKA INST,HUDDINGE HOSP,DEPT PATHOL,S-10401 STOCKHOLM 60,SWEDEN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 91卷 / 03期

关键词：

D O I：

10.1016/0006-291X(79)91938-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The transfer of phospholipids from the endoplasmic reticulum to the inner mitochondrial membrane was investigated by pulse labeling in vivo. With [3H]glycerol microsomal phosphatidylethanolamine and phosphatidylcholine were rapidly labeled during the first 30 min; while maximum incorporation into the inner mitochondrial membrane occurred only after about 5 hours. It appears that the in vivo transfer of these phospholipids between the two membrane compartments is a relatively slow process. © 1979.

引用

页码：709 / 714

页数：6

共 20 条

[1]

AKIYAMA M, 1969, BIOCHIM BIOPHYS ACTA, V187, P105

[2] ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT-LIVER .1. BIOCHEMICAL METHODS [J].

BEAUFAY, H ;

AMARCOST.A ;

FEYTMANS, E ;

THINESSE.D ;

WIBO, M ;

ROBBI, M ;

BERTHET, J .

JOURNAL OF CELL BIOLOGY, 1974, 61 (01) :188-200

[3] BIOGENESIS OF ENDOPLASMIC RETICULUM MEMBRANES .2. SYNTHESIS OF CONSTITUTIVE MICROSOMAL ENZYMES IN DEVELOPING RAT HEPATOCYTE [J].

DALLNER, G ;

SIEKEVITZ, P ;

PALADE, GE .

JOURNAL OF CELL BIOLOGY, 1966, 30 (01) :97-+

[4]

Dallner G, 1974, Methods Enzymol, V31, P191

[5]

DAWSON RMC, 1973, SUB-CELL BIOCHEM, V2, P69

[6]

FOLCH J, 1957, J BIOL CHEM, V226, P497

[7]

GORNALL AG, 1949, J BIOL CHEM, V177, P751

[8]

JELSEMA CL, 1978, J BIOL CHEM, V253, P7960

[9] USE OF PHOSPHOLIPID EXCHANGE PROTEIN TO MEASURE INSIDE-OUTSIDE TRANSPOSITION IN PHOSPHATIDYLCHOLINE LIPOSOMES [J].

JOHNSON, LW ;

HUGHES, ME ;

ZILVERSMIT, DB .

BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 375 (02) :176-185

[10] PHOSPHOLIPID SYNTHESIS AND EXCHANGE IN ISOLATED LIVER CELLS [J].

JUNGALWA.FB ;

DAWSON, RMC .

BIOCHEMICAL JOURNAL, 1970, 117 (03) :481-&

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