CONSTRUCTION OF BEST CONFIDENCE-INTERVALS FOR HALF-LIVES

被引：11

作者：

BARTOSZYNSKI, R ^{[1
]}

POWERS, JD ^{[1
]}

机构：

[1] OHIO STATE UNIV,COLUMBUS,OH 43210

来源：

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS | 1990年 / 13卷 / 01期

关键词：

D O I：

10.1111/j.1365-2885.1990.tb00740.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This paper presents a method of determining a confidence interval for the drug half‐life based on statistical properties of the estimates of the disappearance rate constant of the drug. This interval is shown to be of minimum length which indicates it is a more precise estimate than others currently in use. A computer program to construct these intervals is available upon request. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：1 / 6

页数：6