TOTAL SYNTHESIS OF (+/-)-PEDERAMIDE

被引：55

作者：

ADAMS, MA ^{[1
]}

DUGGAN, AJ ^{[1
]}

SMOLANOFF, J ^{[1
]}

MEINWALD, J ^{[1
]}

机构：

[1] CORNELL UNIV,DEPT CHEM,ITHACA,NY 14853

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1979年 / 101卷 / 18期

关键词：

D O I：

10.1021/ja00512a042

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of ±-pederamide (2), a key intermediate in the projected total synthesis of pederin (1a), a vesicant component of the hemolymph of the staphylinid beetle Paederus fuscipes, is described. The preparation of 2 is accomplished in 16 steps, starting from trans-2-butene epoxide. © 1979, American Chemical Society. All rights reserved.

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页码：5364 / 5370

页数：7

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