(ETA-6-ARENE)CHROMIUM COMPLEXES IN ORGANIC-SYNTHESIS - SYNTHESIS OF (+/-)-DIHYDROXYSERRULATIC ACID

被引：43

作者：

UEMURA, M

NISHIMURA, H

MINAMI, T

HAYASHI, Y

机构：

[1] Osaka City University, Osaka 558, Sugimoto 3-3-138, Sumiyoshi-ku

[2] Sagami Chemical Research Center, Sagamihara, Kanagawa 299

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1991年 / 113卷 / 14期

关键词：

D O I：

10.1021/ja00014a036

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The title compound 1 has been synthesized by utilizing some characteristic properties of (eta-6-arene)chromium complexes. The synthesis of dihydroxyserrulatic acid (1) consists of the following three key steps: (1) nucleophilic addition of a dithianyl group at the meta position to an electron-donating methoxy group, (2) trans arrangement of two benzylic substituents (at C-1 and C-4 positions), and (3) stereocontrol between C-4 and C-11 positions (extracyclic position). These three steps have been realized with high regio- and stereoselectivities by utilizing (arene)chromium complexes.

引用

页码：5402 / 5410

页数：9

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