SYNTHESIS AND PURIFICATION OF OLIGONUCLEOTIDES CONTAINING SULFUR SUBSTITUTED NUCLEOBASES - 4-THIOURACIL, 4-THIOTHYMINE AND 6-MERCAPTOPURINE

被引：37

作者：

CLIVIO, P ^{[1
]}

FOURREY, JL ^{[1
]}

GASCHE, J ^{[1
]}

AUDIC, A ^{[1
]}

FAVRE, A ^{[1
]}

PERRIN, C ^{[1
]}

WOISARD, A ^{[1
]}

机构：

[1] INST JACQUES MONOD,CNRS,PHOTOBIOL MOLEC LAB,F-75251 PARIS 05,FRANCE

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 01期

关键词：

OLIGONUCLEOTIDE; 4-THIOURACIL; 6-MERCAPTOPURINE; GEL ELECTROPHORESIS;

D O I：

10.1016/S0040-4039(00)77674-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A procedure to obtain oligodeoxynucleotides containing sulfur modified nucleobases by standard application of the current phosphoramidite methodology is described as well as their purification technique.

引用

页码：65 / 68

页数：4

共 18 条

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