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MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS ASSOCIATED WITH HEPATITIS-C VIRUS-INFECTION RESPONSIVE TO INTERFERON-ALPHA

被引：61
作者：
YAMABE, H
JOHNSON, RJ
GRETCH, DR
OSAWA, H
INUMA, H
SASAKI, T
KAIZUKA, M
TAMURA, N
TSUNODA, S
FUJITA, Y
SATO, A
ONODERA, K
机构：
[1] UNIV WASHINGTON,DIV NEPHROL,SEATTLE,WA
[2] UNIV WASHINGTON,DEPT LAB MED,SEATTLE,WA
来源：
AMERICAN JOURNAL OF KIDNEY DISEASES | 1995年 / 25卷 / 01期
关键词：
INTERFERON; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; HEPATITIS C VIRUS;
D O I：
10.1016/0272-6386(95)90628-2
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
A 42-year-old man with hepatitis C virus infection, cryoglobulinemia, hypocomplementemia, and nephrotic syndrome is reported. The kidney biopsy showed membranoproliferative glomerulonephritis. The patient was treated with interferon-cy for 2 months. After the treatment, serum hepatitis C virus RNA became negative and nephrotic syndrome remitted. Repeat biopsy of the kidney revealed an improvement in renal histology. This case confirms an association between hepatitis C virus infection and membranoproliferative glomerulonephritis and the usefulness of interferon-a for treatment. (C) 1995 by the National Kidney Foundation, Inc.
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收藏
页码：67 / 69
页数：3
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