THE N-N BOND AS A CHIRAL AXIS - 3-(DIACYLAMINO)QUINAZOLIN-4(3H)ONES AS CHIRAL ACYLATING AGENTS

被引：23

作者：

ATKINSON, RS

BARKER, E

PRICE, CJ

RUSSELL, DR

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 10期

关键词：

D O I：

10.1039/c39940001159

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two diastereoisomers of 3-(diacylamino)quinazolinone 5 are separated and identified by crystal structure determinations which confirm; the presence of an N-N chiral axis: one diastereoisomer of enantiopure 8 reacts with racemic 1-phenylethylamine exclusively at the 2-acetoxypropanoyl imide carbonyl group and with kinetic resolution to give a 3.6:1 ratio of diastereoisomers of 10.

引用

页码：1159 / 1160

页数：2