EFFECTS OF SUPEROXIDE-DISMUTASE ON REPERFUSION ARRHYTHMIAS AND LEFT-VENTRICULAR FUNCTION IN PATIENTS UNDERGOING THROMBOLYSIS FOR ANTERIOR WALL ACUTE MYOCARDIAL-INFARCTION

被引：75

作者：

MUROHARA, Y

YUI, Y

HATTORI, R

KAWAI, C

机构：

[1] Third Division, Department of Internal Medicine, Faculty of Medicine, Kyoto

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1991年 / 67卷 / 08期

关键词：

D O I：

10.1016/0002-9149(91)90538-V

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Oxygen-derived free radicals have been implicated as important factors involved in the genesis of reperfusion injury. There is increasing evidence that a free radical scavenger, superoxide dismutase (SOD), limits reperfusion injury in animal experiments.1,2 We administered human recombinant SOD to patients with anterior wall acute myocardial infarction (AMI) at the time of thrombolysis and investigated (1) if SOD can reduce reperfusion arrhythmias, and (2) if SOD has beneficial effects on left ventricular function in the chronic phase. © 1991.

引用

页码：765 / 767

页数：3

共 6 条

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