DI-N-BUTYLTIN AND DIETHYLTIN MONOFLUOROBENZOATES - SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND INVITRO ANTITUMOR-ACTIVITY

被引：65

作者：

GIELEN, M ^{[1
]}

ELKHLOUFI, A ^{[1
]}

BIESEMANS, M ^{[1
]}

WILLEM, R ^{[1
]}

机构：

[1] FREE UNIV BRUSSELS,CTR HIGH RESOLUT NMR,B-1050 BRUSSELS,BELGIUM

来源：

APPLIED ORGANOMETALLIC CHEMISTRY | 1993年 / 7卷 / 02期

关键词：

ORGANOTIN; SYNTHESIS; MOSSBAUER; H-1; NMR; C-13; ANTITUMOR ACTIVITY;

D O I：

10.1002/aoc.590070206

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The di-n-butyltin(IV) and diethyltin(IV) fluorobenzoates [FCHCOO]2SnR2 and (FC6H4COOR2Sn)2O have been synthesized and characterized spectroscopically. Their in vitro antitumor activity against two human tumor cell lines, MCF-7, a mammary tumor, and WiDr, a colon carcinoma, as well as against the NCI cell panel, is satisfactory.

引用

页码：119 / 125

页数：7

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