SODEFRIN - A FEMALE-ATTRACTING PEPTIDE PHEROMONE IN NEWT CLOACAL GLANDS

被引:188
作者
KIKUYAMA, S
TOYODA, F
OHMIYA, Y
MATSUDA, K
TANAKA, S
HAYASHI, H
机构
[1] NARA MED UNIV, DEPT PHYSIOL, KASHIHARA, NARA 634, JAPAN
[2] RIKEN, RES DEV CORP, WAKO, SAITAMA 35101, JAPAN
[3] NIPPON MED COLL, DEPT PHARMACOL, TOKYO 113, JAPAN
[4] GUNMA UNIV, INST ENDOCRINOL, MAEBASHI, GUMMA 371, JAPAN
[5] GUNMA PREFECTURAL COLL HLTH SCI, MAEBASHI, GUMMA 371, JAPAN
关键词
D O I
10.1126/science.7886452
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A decapeptide called sodefrin was isolated from the abdominal gland of the cloaca of the male red-bellied newt, Cynops pyrrhogaster. The native peptide, as well as the synthetic one, had a female-attracting activity. Sodefrin was found in the apical portion of the epithelial cells of the abdominal gland. Sodefrin is apparently species specific because it did not attract females of Cynops ensicauda. This is the first amphibian pheromone to be identified and the first peptide pheromone identified in a vertebrate.
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页码:1643 / 1645
页数:3
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