ENZYMES IN ORGANIC-SYNTHESIS .36. SYNTHESIS OF OPTICALLY-ACTIVE CIVET CONSTITUENT FROM AN ENZYME-GENERATED CHIRAL SYNTHON

被引：19

作者：

JONES, JB

HINKS, RS

机构：

[1] Department of Chemistry, University of Toronto, Toronto,ON,M5S 1A1, Canada

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1987年 / 65卷 / 04期

关键词：

D O I：

10.1139/v87-119

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A synthesis of the civet constituent, (+)-(S,S)-(cw-6-methyltetrahydropyran-2-yl)acetic acid, is described, in which the key stereochemistry of the chiral starting material is set by an enantiotopically selective, porcine pancreatic lipase-catalyzed, hydrolysis of a meso diester.

引用

页码：704 / 707

页数：4

共 42 条

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