SITE-DIRECTED MUTAGENESIS OF CITRATE SYNTHASE - THE ROLE OF THE ACTIVE-SITE ASPARTATE IN THE BINDING OF ACETYL-COA BUT NOT OXALOACETATE

被引：12

作者：

HANDFORD, PA ^{[1
]}

NER, SS ^{[1
]}

BLOXHAM, DP ^{[1
]}

WILTON, DC ^{[1
]}

机构：

[1] UNIV SOUTHAMPTON,DEPT BIOCHEM,BASSETT CRESCENT E,SOUTHAMPTON SO9 3TU,HANTS,ENGLAND

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1988年 / 953卷 / 03期

关键词：

D O I：

10.1016/0167-4838(88)90030-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：232 / 240

页数：9

共 21 条

[1] EVIDENCE FROM INHIBITOR STUDIES FOR CONFORMATIONAL-CHANGES OF CITRATE SYNTHASE [J].

BAYER, E ;

BAUER, B ;

EGGERER, H .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1981, 120 (01) :155-160

[2] AMINO-ACID-SEQUENCE OF ESCHERICHIA-COLI CITRATE SYNTHASE [J].

BHAYANA, V ;

DUCKWORTH, HW .

BIOCHEMISTRY, 1984, 23 (13) :2900-2905

[3] THE USE OF BACTERIOPHAGE-M13 CARRYING DEFINED FRAGMENTS OF THE ESCHERICHIA-COLI GLTA GENE TO DETERMINE THE LOCATION AND STRUCTURE OF THE CITRATE SYNTHASE PROMOTER REGION [J].

BLOXHAM, DP ;

HERBERT, CJ ;

GILES, IG ;

NER, SS .

MOLECULAR AND GENERAL GENETICS, 1983, 191 (03) :499-506

[4] COMPLETE AMINO-ACID-SEQUENCE OF PORCINE HEART CITRATE SYNTHASE [J].

BLOXHAM, DP ;

PARMELEE, DC ;

KUMAR, S ;

WALSH, KA ;

TITANI, K .

BIOCHEMISTRY, 1982, 21 (09) :2028-2036

[5] PRIMARY STRUCTURE OF PORCINE HEART CITRATE SYNTHASE [J].

BLOXHAM, DP ;

PARMELEE, DC ;

KUMAR, S ;

WADE, RD ;

ERICSSON, LH ;

NEURATH, H ;

WALSH, KA ;

TITANI, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (09) :5381-5385

[6]

EGGERER H, 1965, BIOCHEM Z, V343, P111

[7] RAPID AND EFFICIENT SITE-SPECIFIC MUTAGENESIS WITHOUT PHENOTYPIC SELECTION [J].

KUNKEL, TA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (02) :488-492

[8] CLEAVAGE OF STRUCTURAL PROTEINS DURING ASSEMBLY OF HEAD OF BACTERIOPHAGE-T4 [J].

LAEMMLI, UK .

NATURE, 1970, 227 (5259) :680-+

[9]

LOHLEIN G, 1980, H-S Z PHYSIOL CHEM, V361, P1313

[10] HYSTERETIC BEHAVIOR OF CITRATE SYNTHASE - ALTERNATING SITES DURING THE CATALYTIC CYCLE [J].

LOHLEINWERHAHN, G ;

BAYER, E ;

BAUER, B ;

EGGERER, H .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1983, 133 (03) :665-672

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