INHIBITORY EFFECT OF DIAZOXIDE IN NORMAL TERM LABOR

被引：21

作者：

LANDESMA.R

DESOUZA, FJA

COUTINHO, EM

WILSON, KH

DESOUSA, FMB

机构：

[1] Department of Obstetrics and Gynecology, The New York Hospital-Cornell University Medical Center New York, NY

[2] Department of Obstetrics and Gynecology, Jewish Memorial Hospital, New York, NY

[3] the Department of Biochemistry (Maternidade Climerio de Oliveira), the University of Bahia, Bahia

[4] the Department of Obstetrics (Maternidade Climerio de Oliveira), the University of Bahia, Bahia

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1969年 / 103卷 / 03期

关键词：

D O I：

10.1016/0002-9378(69)90503-1

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Diazoxide, a smooth muscle relaxant, was administered to 16 patients with intact membranes in normal term labor. The drug reduced both the intensity and the frequency of uterine contractions in a direct relationship to the amount administered. The cardiovascular effects were a dose-related rise in maternal heart rate and a transient hypotension which was dependent on individual sensitivity to the drug. No adverse effects on the fetus were observed. The ability of diazoxide to inhibit myometrial activity may be of therapeutic value. © 1969.

引用

页码：430 / &

共 5 条

[1]

COUTINHO EM, 1967, 8 P INT PLANN PAR WO, V8, P432

[2] CLINICAL EVALUATION OF DIAZOXIDE - A NEW TREATMENT FOR ACUTE HYPERTENSION [J].

FINNERTY, FA ;

MAGILL, J ;

TUCKMAN, J ;

KAKAVIATOS, N .

CIRCULATION, 1963, 28 (02) :203-&

[3] RELAXANT EFFECT OF DIAZOXIDE ON ISOLATED GRAVID AND NONGRAVID HUMAN MYOMETRIUM [J].

LANDESMAN, R ;

WILSON, KH .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1968, 101 (01) :120-+

[4]

LANDESMAN R, IN PRESS

[5]

WOHL AJ, 1967, J PHARMACOL EXPER TH, P53

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